Receptor
PD-1
Programmed Death-1: inhibitory receptor on activated/exhausted T cells (and NK cells).
Also called: programmed death 1, CD279, PDCD1
In short
- 1What it is: a receptor in molecules and receptors.
- 2How it connects: acts on 2 and is affected by 4 concepts — mostly 1 cell, 1 molecule, 1 pathway.
- 3Where it sits: recognition, failure, target on the 15-step immune chain.
What it does
Anti-PD-1 (pembrolizumab, nivolumab) is the most widely used checkpoint blockade.
Its connections at a glance
Each dot is a concept directly linked to PD-1. Colours show the kind of concept.
Sources & evidenceloading…
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Graph ID R011 · concept status: established. Select any connection above to inspect evidence for that specific link.