Biomarker
PD-L1 expression
Tumour PD-L1 expression by immunohistochemistry (IHC): TPS (tumour proportion score: % tumour cells staining ≥1+) for NSCLC/HNSCC; CPS (combined positive score: PD-L1+ tumour + immune + stromal cells per 100 tumour cells) for TNBC/gastric/cervical/endometrial.
Also called: PD-L1 IHC, PD-L1 TPS, PD-L1 CPS
In short
- 1What it is: a biomarker in research methods.
- 2How it connects: acts on 2 and is affected by 0 concepts — mostly 1 receptor, 1 therapy.
- 3Where it sits: biomarker, target on the 15-step immune chain.
What it does
NSCLC: TPS ≥50% → pembrolizumab monotherapy first-line (KEYnote-024: OS HR 0.62).
Its connections at a glance
Each dot is a concept directly linked to PD-L1 expression. Colours show the kind of concept.
Learn next
Sources & evidenceloading…
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Graph ID B011 · concept status: established. Select any connection above to inspect evidence for that specific link.