Disease
Systemic lupus erythematosus
Systemic autoimmune disease with immune-complex and interferon-associated biology.
Also called: SLE, lupus, systemic lupus erythematosus
In short
- 1What it is: a disease in diseases and immunopathology.
- 2How it connects: acts on 2 and is affected by 11 concepts — mostly 5 molecule, 2 pathway, 1 disease.
- 3Where it sits: failure, disease on the 15-step immune chain.
What it does
NET→pDC→IFN-α→BAFF→autoreactive B cell rescue→Tfh→GC→anti-dsDNA→IC deposition→LN.
Its connections at a glance
Each dot is a concept directly linked to Systemic lupus erythematosus. Colours show the kind of concept.
Sources & evidenceloading…
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Graph ID D007 · concept status: established. Select any connection above to inspect evidence for that specific link.