Therapy
Adalimumab
Monoclonal antibody targeting TNF.
Also called: adalimumab, Humira, ADA
In short
- 1What it is: a therapy in therapies and applications.
- 2How it connects: acts on 2 and is affected by 0 concepts — mostly 1 molecule, 1 therapy.
- 3Where it sits: therapy on the 15-step immune chain.
What it does
Fully human IgG1 SC; binds soluble+membrane TNF; broadest approved indication (RA, PsA, AS, CD/UC, psoriasis, JIA, uveitis, HS); anti-drug antibody (ADA) rate 25-40% (reduced with concomitant MTX); preferred in pregnancy over infliximab (later switch: both cross placenta via FcRn → avoid live vaccines in infant for 6 months); biosimilars available
Its connections at a glance
Each dot is a concept directly linked to Adalimumab. Colours show the kind of concept.
Learn next
Sources & evidenceloading…
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Graph ID I002 · concept status: established. Select any connection above to inspect evidence for that specific link.