Cell
Th2 cell
Type-2 immunity; associated with IL-4, IL-5 and IL-13.
Also called: Th2 cell, T helper 2
In short
- 1What it is: a cell in cells and organs.
- 2How it connects: acts on 5 and is affected by 3 concepts — mostly 1 cell, 5 molecule, 1 pathway.
- 3Where it sits: response, failure, target on the 15-step immune chain.
What it does
IL-4 → IgE class switching; IL-5 → eosinophil activation; IL-13 → mucus/bronchoconstriction; helminth expulsion in normal biology; misdirected at harmless allergens in atopy; dupilumab (anti-IL-4Rα: blocks IL-4 and IL-13 simultaneously via shared Type II receptor, mechanistic basis of its breadth across AD, asthma, CRSwNP, EoE)
Its connections at a glance
Each dot is a concept directly linked to Th2 cell. Colours show the kind of concept.
Sources & evidenceloading…
Loading reviewed sources…
Graph ID C012 · concept status: established. Select any connection above to inspect evidence for that specific link.