Molecule
IL-13
Type-2 cytokine associated with mucus production, tissue responses and fibrosis-associated biology.
Also called: interleukin-13, IL-13, IL13
In short
- 1What it is: a molecule in molecules and receptors.
- 2How it connects: acts on 3 and is affected by 2 concepts — mostly 3 cell, 1 disease, 1 biomarker.
- 3Where it sits: signalling, response, target on the 15-step immune chain.
What it does
Goblet cell hyperplasia (mucus overproduction); smooth muscle hyperresponsiveness; FLG (filaggrin) downregulation (→ atopic march: skin sensitisation → food allergy → rhinitis → asthma); eotaxin production (eosinophil recruitment); blocked by dupilumab (anti-IL-4Rα Type II receptor)
Its connections at a glance
Each dot is a concept directly linked to IL-13. Colours show the kind of concept.
Sources & evidenceloading…
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Graph ID M009 · concept status: established. Select any connection above to inspect evidence for that specific link.