Pathway
Class switching & somatic hypermutation
AID-dependent isotype switching and affinity maturation in germinal centres.

In short
- 1What it is: a pathway in signalling and mechanisms.
- 2How it connects: acts on 1 and is affected by 4 concepts — mostly 1 cell, 2 molecule, 1 pathway.
- 3Where it sits: response on the 15-step immune chain.
What it does
CD40L or AID deficiency → hyper-IgM syndrome.
Its connections at a glance
Each dot is a concept directly linked to Class switching & somatic hypermutation. Colours show the kind of concept.
Sources & evidenceloading…
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Graph ID P018 · concept status: established. Select any connection above to inspect evidence for that specific link.