Therapy
Tezepelumab
Human IgG2λ anti-TSLP mAb: blocks TSLP (thymic stromal lymphopoietin) the upstream epithelial alarmin.
Also called: Tezspire, anti-TSLP
In short
- 1What it is: a therapy in therapies and applications.
- 2How it connects: acts on 2 and is affected by 1 concepts — mostly 1 molecule, 1 disease, 1 trial.
- 3Where it sits: therapy, trial on the 15-step immune chain.
What it does
NAVIGATOR trial (N=1061): 56% exacerbation reduction vs placebo in severe asthma across all endotypes (including low-eosinophil, triple-negative for other biologics).
Its connections at a glance
Each dot is a concept directly linked to Tezepelumab. Colours show the kind of concept.
Sources & evidenceloading…
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Graph ID I022 · concept status: established. Select any connection above to inspect evidence for that specific link.