Receptor
MHC class II (HLA-DR/DQ/DP)
Presents endocytosed peptides to CD4 T cells; strongest genetic risk locus for many autoimmune diseases.
In short
- 1What it is: a receptor in foundations.
- 2How it connects: acts on 2 and is affected by 3 concepts — mostly 1 cell, 1 pathway, 2 biomarker.
- 3Where it sits: recognition on the 15-step immune chain.
What it does
HLA-DRB1 shared epitope (RA), HLA-DQ2/DQ8 (coeliac, T1D).
Its connections at a glance
Each dot is a concept directly linked to MHC class II (HLA-DR/DQ/DP). Colours show the kind of concept.
Sources & evidenceloading…
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Graph ID R026 · concept status: established. Select any connection above to inspect evidence for that specific link.