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Receptor

TCR

T cell receptor: αβ heterodimer (or γδ) + CD3 complex (ε,γ,δ,ζ).

Also called: T cell receptor, αβ TCR, γδ TCR

Ask about TCR See in graph Sources

In short

  1. 1What it is: a receptor in molecules and receptors.
  2. 2How it connects: acts on 1 and is affected by 2 concepts — mostly 2 pathway, 1 ai method.
  3. 3Where it sits: recognition on the 15-step immune chain.

What it does

CAR (chimeric antigen receptor) replaces TCR variable regions with antibody-derived scFv → MHC-independent recognition (bypasses MHC-I downregulation cancer escape); tebentafusp = TCR-based bispecific (gp100/HLA-A*02:01 × CD3)

Its connections at a glance

Each dot is a concept directly linked to TCR. Colours show the kind of concept.

V(D)J recombinationStructure prediction …T-cell receptor signa…TCR

Learn next

Comes beforeV(D)J recombinationPathwayComes beforeStructure prediction (AlphaFold-class)AI methodLeads toT-cell receptor signallingPathway
Sources & evidenceloading…

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Graph ID R016 · concept status: established. Select any connection above to inspect evidence for that specific link.