Pathway
Co-stimulation (signal 2)
CD28–CD80/86 engagement licenses naive T cells; absent signal 2 leads to anergy.
In short
- 1What it is: a pathway in signalling and mechanisms.
- 2How it connects: acts on 1 and is affected by 1 concepts — mostly 1 cell, 1 receptor.
- 3Where it sits: signalling on the 15-step immune chain.
Its connections at a glance
Each dot is a concept directly linked to Co-stimulation (signal 2). Colours show the kind of concept.
Sources & evidenceloading…
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Graph ID P014 · concept status: established. Select any connection above to inspect evidence for that specific link.