Molecule
IL-5
Promotes eosinophil growth, recruitment and activation.
Also called: interleukin-5, IL-5, IL5
In short
- 1What it is: a molecule in molecules and receptors.
- 2How it connects: acts on 2 and is affected by 3 concepts — mostly 3 cell, 1 receptor, 1 therapy.
- 3Where it sits: response, target on the 15-step immune chain.
What it does
Eosinophil growth, differentiation, activation, survival; target of mepolizumab (anti-IL-5; MENSA: exacerbation -53% in severe eosinophilic asthma) and reslizumab (anti-IL-5); EGPA (eosinophilic granulomatosis with polyangiitis), HES, severe asthma
Its connections at a glance
Each dot is a concept directly linked to IL-5. Colours show the kind of concept.
Sources & evidenceloading…
Loading reviewed sources…
Graph ID M008 · concept status: established. Select any connection above to inspect evidence for that specific link.