Cell
Follicular dendritic cell
Germinal-centre stromal cell that displays native antigen to B cells.
Also called: FDC, follicular dendritic cell
In short
- 1What it is: a cell in cells and organs.
- 2How it connects: acts on 2 and is affected by 0 concepts — mostly 1 cell, 1 pathway.
- 3Where it sits: response on the 15-step immune chain.
What it does
Displays native antigen in GC → positive selection of highest-affinity B cells (Darwinian selection within lymph node); drives autoreactive B cell affinity maturation in SLE; interlocks with Tfh-B cell collaboration
Its connections at a glance
Each dot is a concept directly linked to Follicular dendritic cell. Colours show the kind of concept.
Sources & evidenceloading…
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Graph ID C020 · concept status: established. Select any connection above to inspect evidence for that specific link.