Layer 05 · System simulator

Watch the system run

A teaching model, in normalised units. Pick a host state, then change the pathogen, the arms of immunity and the treatments, and see which outcome follows.

6HOST STATES

10PARAMETERS

4TREATMENTS

Host states

Innate effectors contain early growth; adaptive effectors clear the pathogen after a ~4-day lag; regulation returns the system to baseline.

Cleared: the infection resolves without severe damage. Cleared on day 6.7.

PathogenInnate cellsCytokinesAdaptive cellsRegulationTissue damageT-cell exhaustionMemory pool

Infection and immunity

Starting dose of pathogen 0.050Pathogen growth rate 1.20Innate strength (neutrophils) 1.00Adaptive strength (T and B cells) 1.00Cytokine gain 1.00Regulation (Tregs, IL-10) 1.00Prior memory (vaccination) 0.00Days until adaptive response 4.00T-cell exhaustion tendency (chronic antigen) 1.00Re-infection day (0 = none) 0.00

Treatments

Antibiotic / antiviral

Steroid

Anti-cytokine (e.g. anti-IL-6)

Checkpoint inhibitor

A teaching model in normalised units, not a clinical prediction.