Tissue
Granuloma
Organized inflammatory structure important for containment of some persistent pathogens.
Also called: granuloma, caseating granuloma, non-caseating granuloma
In short
- 1What it is: a tissue in cells and organs.
- 2How it connects: acts on 1 and is affected by 3 concepts — mostly 3 molecule, 1 data.
- 3Where it sits: response, failure on the 15-step immune chain.
What it does
Organised immune structure containing intracellular pathogens (TB, fungal, Nocardia); TNF essential for granuloma integrity (anti-TNF → granuloma dissolution → TB reactivation → mandatory LTBI screening before anti-TNF); sarcoidosis: non-caseating granuloma without identified organism
Its connections at a glance
Each dot is a concept directly linked to Granuloma. Colours show the kind of concept.
Sources & evidenceloading…
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Graph ID T008 · concept status: established. Select any connection above to inspect evidence for that specific link.