Tissue
Synovium
Joint tissue central to rheumatoid arthritis pathology.
Also called: synovial membrane, synovium, joint, articular cavity
Sparsely connected — only 1 link recorded so far.

In short
- 1What it is: a tissue in cells and organs.
- 2How it connects: acts on 1 and is affected by 0 concepts — mostly 1 disease.
- 3Where it sits: failure, disease on the 15-step immune chain.
What it does
RA pathological focus: CD68+ macrophage density in synovial lining layer correlates with DAS28; FLS (fibroblast-like synoviocytes) invasion + pannus + RANKL-osteoclast → joint erosion; R4RA AI pathotyping: lymphoid/myeloid/fibroid synovial pathotypes predict biologic response
Its connections at a glance
Each dot is a concept directly linked to Synovium. Colours show the kind of concept.
Learn next
Sources & evidenceloading…
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Graph ID T006 · concept status: established. Select any connection above to inspect evidence for that specific link.