Molecule
IgG
Class-switched, high-affinity immunoglobulin: produced by plasma cells (bone marrow-resident long-lived, and short-lived GC-derived).
Also called: immunoglobulin G, serum IgG, IgG1, IgG4
In short
- 1What it is: a molecule in molecules and receptors.
- 2How it connects: acts on 1 and is affected by 4 concepts — mostly 1 cell, 1 pathway, 1 disease.
- 3Where it sits: response, biomarker on the 15-step immune chain.
What it does
Secondary antibody deficiency: anti-CD20 (rituximab/ocrelizumab) repeated courses → IgG <5g/L → recurrent infections → SCIG replacement needed.
Its connections at a glance
Each dot is a concept directly linked to IgG. Colours show the kind of concept.
Sources & evidenceloading…
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Graph ID M024 · concept status: established. Select any connection above to inspect evidence for that specific link.