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Therapy

Eculizumab

Blocks C5 cleavage → no C5a or MAC.

Ask about Eculizumab See in graph Sources

In short

  1. 1What it is: a therapy in therapies and applications.
  2. 2How it connects: acts on 4 and is affected by 1 concepts — mostly 1 molecule, 2 disease, 1 pathogen.
  3. 3Where it sits: therapy on the 15-step immune chain.

What it does

PNH, aHUS, AQP4+ NMOSD, gMG; requires meningococcal vaccination.

Its connections at a glance

Each dot is a concept directly linked to Eculizumab. Colours show the kind of concept.

PNH eculizumab (TRIUM…Complement C5 / C5a /…Paroxysmal nocturnal …Neuromyelitis optica …Neisseria meningitidisEculizumab

Learn next

Comes beforePNH eculizumab (TRIUMPH)TrialLeads toParoxysmal nocturnal haemoglobinuriaDiseaseLeads toNeuromyelitis optica spectrum disorderDisease
Sources & evidenceloading…

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Graph ID I027 · concept status: established. Select any connection above to inspect evidence for that specific link.