Disease
Chronic granulomatous disease
Defective phagocyte oxidative burst with susceptibility to recurrent infections.
Also called: CGD, chronic granulomatous disease, phagocyte NADPH oxidase deficiency
In short
- 1What it is: a disease in diseases and immunopathology.
- 2How it connects: acts on 3 and is affected by 0 concepts — mostly 2 cell, 1 molecule.
- 3Where it sits: failure, disease on the 15-step immune chain.
What it does
CYBB/gp91phox (X-linked, 70%); NCF1/p47phox autosomal recessive; DHR flow cytometry diagnostic (no fluorescence shift on PMA stimulation = CGD); susceptibility to catalase-positive organisms only (S.
Its connections at a glance
Each dot is a concept directly linked to Chronic granulomatous disease. Colours show the kind of concept.
Sources & evidenceloading…
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Graph ID D009 · concept status: established. Select any connection above to inspect evidence for that specific link.