Molecule
Perforin / Granzyme B
Pore-forming protein and serine protease delivered by CTL and NK cells to induce target apoptosis.
In short
- 1What it is: a molecule in molecules and receptors.
- 2How it connects: acts on 1 and is affected by 2 concepts — mostly 3 cell.
- 3Where it sits: consequence on the 15-step immune chain.
What it does
Perforin deficiency causes familial HLH.
Its connections at a glance
Each dot is a concept directly linked to Perforin / Granzyme B. Colours show the kind of concept.
Sources & evidenceloading…
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Graph ID M031 · concept status: established. Select any connection above to inspect evidence for that specific link.