Biomarker
Serum IgE
Immunoglobulin associated with allergic/type-2 immune responses.
Also called: total IgE, serum IgE, immunoglobulin E
Sparsely connected — only 1 link recorded so far.
In short
- 1What it is: a biomarker in research methods.
- 2How it connects: acts on 1 and is affected by 0 concepts — mostly 1 molecule.
- 3Where it sits: biomarker, failure on the 15-step immune chain.
What it does
IgE class switching driven by IL-4; elevated in allergy, parasitic infection, IgE myeloma (rare); omalizumab dosing based on baseline total IgE level; clinical note: total IgE rises during omalizumab treatment (drug-bound IgE detectable) → measure free IgE not total IgE to monitor omalizumab response; tryptase + IgE elevated → confirms mast cell-mediated anaphylaxis vs other causes
Its connections at a glance
Each dot is a concept directly linked to Serum IgE. Colours show the kind of concept.
Sources & evidenceloading…
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Graph ID B004 · concept status: established. Select any connection above to inspect evidence for that specific link.